Position

As Lead Scientist, you will work within the Research and Development Processing Team. This team is responsible for the development of new processes for medical isotopes. As Lead Scientist, you are responsible for the development of innovative processes and for performing an effective set of experiments to achieve good quality. You coordinate lab staff in a project-based manner, provide input to process engineers for the development of process equipment, and, together with the project manager, determine which activities are necessary for a good process- and product quality. You will report to the R&D manager Advancing Nuclear Medicine.

Within the Research and Development Processing Team, you will be responsible for the development of the entire process to make a new medical isotope. From qualification of the enriched material for irradiation, development of the purification process after irradiation, to qualification of the developed isotope for the preparation of end products. For the latter, you are in regular contact with partners who develop end products. You are driven to find out what they anticipate they will need to develop good end products, and can justify internally when extra work is needed and motivate your colleagues for this. You oversee the consequences of steps early in the chain, or of lateral processes, on the quality of the product, and are solution-oriented to come to a renewed approach to the project.

From a ‘prototype process’ level the projects need to be scaled up, automated and optimised by the Commercial Processing Team. As Lead Scientist, at the current stage of the project, you have the responsibility to develop a robust process, that is to say a standard and reliable process with consistent product quality. The final goal of the developments is implementation in the GMP (Good Manufacturing Practices) FIELD-LAB facilities and the supply of medical isotopes to partners or customers for the preparation of end products.

Together with the project team, you will be responsible for:

Bench-to-bedside development of new medical isotopes in collaboration with academic and industrial partners;

From a prototype process in the R&D lab, and a robust process, to the transfer and implementation of the process in the FIELD-LAB GMP facilities;

Scaling up, automating and optimising the process to deliver commercial quantities to the market in the future.

As Lead Scientist medical isotopes, you will be tasked with defining and securing the content quality within the project in line with the project objectives. This requires a combination of substantive understanding and steering where necessary with (project) management, focused on the market perspective. You are aware of developments in the field, including preclinical, clinical and commercial areas, and share relevant developments with the team. Of importance for the GMP implementation of the developed process is writing and reviewing, and documenting of relevant information from the development and verification of the processes.

You also play an important role in ensuring safety in the work to be performed. Within NRG’s complex nuclear environment, you know how to properly inform and motivate all those involved in the project in order to achieve the project’s goal. In doing so, you take into account the interaction between the various stakeholders and direct the project on the basis of content.

What awaits you as Lead Scientist medical isotopes:

• As Lead Scientist medical isotopes, you will be given challenging projects with great personal responsibility, where end-user requirements combined with strict safety and quality requirements are of great importance;
• We want you to learn from the experts in the field. You will therefore work closely with staff from the FIELD-LAB team, within NRG and with external parties;
• A personal development plan will also be drawn up and designed together with you;
• Enthusiastic colleagues and a good team atmosphere.